Be patient. I leave my F/T rats out for a couple of hours then run them under hot tap water. If it feels squishy, kinds of like rare steak, then I just drop it in. If Roxy doesn't eat it within 24 hours I remove it and wait a couple of days. I figure either I didn't defrost it right or she just isn't that hungry. But I don't want her to eat spoiled food and they can smell nasty!!! Good luck. It may take a while but you are much better off switching to the frozen rats.