I have been battling mites since summer began. I use mite off as directed by the bottle. Take all funiture and substate out. Though out substrate (paper towl) and clean and soak furniture for an hour. Clean and soak encloser for same length for time as furniture. While soaking the encloser I rinse the snakes off in warm water to get the mites off of them that I see crawling around. Then put it all back together and start the prosses over in a week. Because that's when I see the mites again. So far it has not spread to the rest of my collection because I have the infected herps in quatine and out of the same room as the rest. I aslo handle the infected herps last and wash my hands and arms thoughlty and change my clothes just in case I have to go back and handle the other herps again.